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INTRODUCTION
Imatinib (Imatinib mesylate 400mg) Tablet belongs to the class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of blood cancer (chronic myeloid leukaemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor.
Imatinib Tablet should be taken with food, but better to have it same time every day to get the most benefit. Swallow it as a whole. Do not chew, crush or break it. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Many other medicines can affect, or be affected by this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
USES OF IMATINIB TABLET
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- Blood cancer (Chronic myeloid leukaemia)
- Blood cancer (Acute lymphocytic leukemia)
- Gastrointestinal stromal tumour
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BENEFIT OF IMATINIB TABLET
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- Blood cancer (Chronic myeloid leukaemia)
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Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body’s ability to fight infection. Imatinib Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
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- Blood cancer (Acute lymphocytic leukemia)
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Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Imatinib Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
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- Gastrointestinal stromal tumour
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A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Imatinib Tablet helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.
SIDE EFFECT OF IMATINIB TABLET
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine
Common Side Effects Of Imatinib: –
- Edema (swelling).
- Nausea.
- Vomiting.
- Muscle cramp.
- Musculoskeletal (bone, muscle or joint) pain.
- Diarrhea.
- Rash.
- Fatigue.
- Abdominal pain.
SAFETY ADVICE
Imatinib Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. It is also unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Lactating women should not breastfeed while using this drug and one month after stopping it. Imatinib Tablet should be used with caution in patients with kidney and liver disease. Dose adjustment of Imatinib Tablet may be needed for these patients. Imatinib Tablet may cause side effects which could affect your ability to drive.
WHAT IF YOU FORGET TO TAKE IMATINIB TABLET
If you miss a dose of Imatinib Tablet take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
